With the first weekend of November in the books, the 2024 NFL season surges ahead toward a 14-game slate for Week 10. This week features a bunch of good games — four of which are divisional tilts — so bettors will be lining up for opportunities to attack the moneyline, spread and over/under offerings this weekend.
Successful sports betting requires research and knowledge, so knowing the opening lines at the beginning of the week and tracking the movement in the ensuing days can be crucial. This column aims to inform bettors of the opening odds, shifts throughout the week, and noteworthy action and activity going into the weekend.
Checking this column early and often each week helps you identify value wagers, recognize betting trends, and understand how oddsmakers think. When you make studying and analyzing the lines part of your routine, don’t be surprised if you start seeing more consistent returns on your investments.
Of course, there’s more to winning than just knowing the odds. Be sure to also check SN’s best bets, primetime game predictions, and weekly pick’em columns throughout the week. The Jugo Mobile has all the resources you need to become a more confident, informed, and successful sports bettor.
Let’s get to the moneyline, spread, and over/under odds for every matchup on the Week 10 schedule We’ll then break down the early values, top storylines, and props to target from the upcoming weekend’s games.
NFL Week 10 odds: Lines, spreads, over/under totals
All odds courtesy of BetMGM.
| Day/time (ET) | Game | ML | ATS | O/U |
| Thu., 11/78:15 p.m. | Bengals @Ravens | BAL -250;CIN +200 | BAL -6 (-115)CIN +6 (-105) | O 52.5 (-110)U 52.5 (-110) |
| Sun., 11/109:30 a.m. | Giants vs.Panthers* | NYG -225CAR +180 | NYG -4.5 (-110)CAR +4.5 (-110) | O 42.5 (-105)U 42.5 (-115) |
| Sun., 11/101:00 p.m. | Patriots @Bears | CHI -350NE +280 | CHI -7 (-110)NE +7 (-110) | O 39.5 (-110)U 39.5 (-110) |
| Sun., 11/101:00 p.m. | Bills @Colts | BUF -225IND +180 | BUF -4.5 (-110)IND +4.5 (-110) | O 47 (-110)U 47 (-110) |
| Sun., 11/101:00 p.m. | Vikings @Jaguars | MIN -210JAX +170 | MIN -4 (-110)JAX +4 (-110) | O 46.5 (-110)U 46.5 (-110) |
| Sun., 11/101:00 p.m. | Broncos @Chiefs | KC -450DEN +350 | KC -9.5 (-110)DEN +9.5 (-110) | O 42.5 (-110)U 42.5 (-110) |
| Sun., 11/101:00 p.m. | Falcons @Saints | ATL -185NO +150 | ATL -3 (-120)NO +3 (+100) | O 47.5 (-110)U 47.5 (-110) |
| Sun., 11/101:00 p.m. | 49ers @Buccaneers | SF -275TB +210 | SF -6.5 (-110)TB +6.5 (-110) | O 48.5 (-110)U 48.5 (-110) |
| Sun., 11/101:00 p.m. | Steelers @Commanders | WAS -140PIT +115 | WAS -2.5 (-110)PIT +2.5 (-110) | O 44.5 (-110)U 44.5 (-110) |
| Sun., 11/104:05 p.m. | Titans @Chargers | LAC -400TEN +325 | LA -7.5 (-115)TEN +7.5 (-105) | O 38 (-110)U 38 (-110) |
| Sun., 11/104:25 p.m. | Jets @Cardinals | ARI -120NYJ +100 | ARI -1.5 (-110)NYJ +1.5 (-110) | O 45 (-110)U 45 (-110) |
| Sun., 11/104:25 p.m. | Eagles @Cowboys | PHI -300DAL +240 | PHI -6.5 (-110)DAL +6.5 (-110) | O 44.5 (-110)U 44.5 (-110) |
| Sun., 11/108:20 p.m. | Lions @ Texans | DET -210HOU +170 | DET -4 (-110)HOU +4 (-110) | O 48.5 (-110)U 48.5 (-110) |
| Mon., 11/118:15 p.m. | Dolphins @Rams | LAR -140MIA +115 | LAR -2.5 (-115)MIA +2.5 (-105) | O 50.5 (-110)U 50.5 (-110) |
* Germany game
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